Tuesday, September 27, 2016

Bontril PDM


Pronunciation: FEN-dye-MET-ra-zeen
Generic Name: Phendimetrazine
Brand Name: Bontril PDM


Bontril PDM is used for:

The short-term management of obesity combined with a diet and exercise program.


Bontril PDM is an anorectic. Exactly how Bontril PDM works is unknown, although one of its effects is to decrease your appetite.


Do NOT use Bontril PDM if:


  • you are allergic to any ingredient in Bontril PDM

  • you have heart disease; glaucoma; an overactive thyroid; moderate, severe, or uncontrolled high blood pressure; or a history of drug abuse; or you are highly nervous or agitated.

  • you are taking guanadrel or guanethidine, or you have taken furazolidone or a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.



Before using Bontril PDM:


Some medical conditions may interact with Bontril PDM. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have diabetes or high blood pressure

Some MEDICINES MAY INTERACT with Bontril PDM. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Furazolidone or MAOIs (eg, phenelzine) because the risk of severe high blood pressure, irregular heartbeat, high fever, tremors, and seizures may be increased

  • Guanadrel or guanethidine because their effectiveness may be decreased by Bontril PDM

This may not be a complete list of all interactions that may occur. Ask your health care provider if Bontril PDM may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Bontril PDM:


Use Bontril PDM as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Take Bontril PDM about 1 hour before meals. Take your last dose of the day at least 4 to 6 hours before bedtime.

  • If you miss a dose of Bontril PDM and you are taking it regularly, take it as soon as possible. If several hours have passed or if it is nearing time for the next dose, do not double the dose to catch up, unless advised by your health care provider. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Bontril PDM.



Important safety information:


  • Bontril PDM may cause dizziness or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Bontril PDM with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

  • Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.

  • Some of these products may contain tartrazine dye (FD&C Yellow No. 5). This may cause an allergic reaction in some patients. If you have ever had an allergic reaction to tartrazine, ask your pharmacist if your product has tartrazine in it.

  • Diabetes patients - Bontril PDM may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.

  • Tell your doctor or dentist that you take Bontril PDM before you receive any medical or dental care, emergency care, or surgery.

  • Bontril PDM should not be used in CHILDREN younger than 12 years old; safety and effectiveness in these children have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Bontril PDM while you are pregnant. It is not known if Bontril PDM is found in breast milk. If you are or will be breast-feeding while you use Bontril PDM, check with your doctor. Discuss any possible risks to your baby.

When used for long periods of time or at high doses, Bontril PDM may not work as well and may require higher doses to obtain the same effect as when originally taken. This is known as TOLERANCE. Talk with your doctor if Bontril PDM stops working well. Do not take more than prescribed.


When used for longer than a few weeks or at high doses, some people develop a need to continue taking Bontril PDM. This is known as DEPENDENCE or addiction.


If you suddenly stop taking Bontril PDM, you may experience WITHDRAWAL symptoms including extreme fatigue and depression.



Possible side effects of Bontril PDM:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Agitation; blurred vision; constipation; diarrhea; dizziness; dry mouth; flushing; headache; nausea; nervousness; overstimulation; restlessness; trouble sleeping.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); changes in sex drive; fast or irregular heartbeat; frequent urination or trouble urinating; hallucinations; seizures; severe headache or dizziness; stomach pain; sweating; tremor; unusual behavior or personality changes.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Bontril PDM side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include coma; confusion; diarrhea; nausea; panic attack; rapid breathing; seizures; severe restlessness; stomach cramps; tremor; vomiting.


Proper storage of Bontril PDM:

Store Bontril PDM at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Bontril PDM out of the reach of children and away from pets.


General information:


  • If you have any questions about Bontril PDM, please talk with your doctor, pharmacist, or other health care provider.

  • Bontril PDM is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Bontril PDM. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Bontril PDM resources


  • Bontril PDM Side Effects (in more detail)
  • Bontril PDM Use in Pregnancy & Breastfeeding
  • Drug Images
  • Bontril PDM Drug Interactions
  • Bontril PDM Support Group
  • 2 Reviews for Bontril PDM - Add your own review/rating


  • Bontril PDM Concise Consumer Information (Cerner Multum)

  • Bontril PDM Advanced Consumer (Micromedex) - Includes Dosage Information

  • Phendimetrazine Prescribing Information (FDA)

  • Phendimetrazine Tartrate Monograph (AHFS DI)



Compare Bontril PDM with other medications


  • Obesity

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